Curr Pharm Des. 2009;15(36):4094-102.

Polyunsaturated fatty acids and cardiovascular disease.

Calzolari I, Fumagalli S, Marchionni N, Di Bari M.

Source

Department of Critical Care Medicine and Surgery, Unit of Gerontology and Geriatrics, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

Abstract

Several observational and experimental studies show the beneficial effects of omega-3 poly-unsaturated fatty acids (PUFA) in cardiovascular disease. The results from such studies justify supplementation of omega-3 PUFA in primary and secondary prevention of several clinical conditions, including coronary heart disease, sudden cardiac death and heart failure. Supplementation of omega-3 PUFA is also indicated as monotherapy in the treatment of hypertriglyceridemia. Analysis of their biological actions suggests a variety of anti-arrhythmic, anti-thrombotic, anti-atherosclerotic and anti-inflammatory mechanisms underlying their clinical benefits.

PMID:: 20041811; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

Fatty Acids, Omega-3

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Dietary Fats - MedlinePlus Health Information

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