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Clin Neuropathol. 2010 Jan-Feb;29(1):9-13.

Intracranial extension of salivary gland tumors.

Author information

  • 1Department of Neurological Sciences, Neurosurgical Clinic, Federico II University, Naples, Italy. frmaiuri@yahoo.it

Abstract

OBJECTIVE:

The aim of this report is to describe 3 cases of salivary gland tumors with intracranial extension associated to an extracerebral mass lesion, and to discuss the frequence, pathology and treatment of these very rare localizations.

CLINICAL MATERIAL:

The 3 patients were 1 woman and 2 men, aged 44, 53 and 74 years, respectively. The primary tumors were an adenocarcinoma and a malignant oncocytoma of the parotid gland and an adenoid cystic carcinoma of the submandibular gland. The location of the intradural extra-axial tumor was the middle fossa and temporal region in 2 cases and the cerebellopontine angle in 1. Surgical treatment consisted in the seemingly complete removal of 2 tumors with middle fossa localization and partial removal of the cerebellopontine angle lesion. Radiotherapy was administered in all 3 cases and chemotherapy in 2.

RESULTS:

1 patient is alive and free of recurrence 32 months after removal of the intracranial tumor; 2 other patients died 28 months and 12 months postoperatively.

CONCLUSIONS:

The intracranial extension of salivary gland tumors is a very rare event. An aggressive surgical resection followed by radiotherapy is justified in cases with significant intracranial mass lesions and scarce bone and dural involvement.

PMID:
20040327
[PubMed - indexed for MEDLINE]
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