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Br J Cancer. 2010 Jan 19;102(2):243-8. doi: 10.1038/sj.bjc.6605497. Epub 2009 Dec 22.

Whole-genome cancer analysis as an approach to deeper understanding of tumour biology.

Author information

  • 1J Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD 20850, USA. RLS@jcvi.org

Abstract

Recent advances in DNA sequencing technology are providing unprecedented opportunities for comprehensive analysis of cancer genomes, exomes, transcriptomes, as well as epigenomic components. The integration of these data sets with well-annotated phenotypic and clinical data will expedite improved interventions based on the individual genomics of the patient and the specific disease.

PMID:
20029419
[PubMed - indexed for MEDLINE]
PMCID:
PMC2816661
Free PMC Article
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