Childhood psoriasis: often favorable outcome

Prescrire Int. 2009 Dec;18(104):275.

Abstract

(1) Plaque psoriasis is the most common form of psoriasis in children. Topical agents should be tried first, especially well-tolerated products such as emollients. Topical corticosteroids are sometimes useful during exacerbations but, given adverse effects, they should only be used for short periods; (2) UVB phototherapy is an option for extensive psoriasis refractory to local treatments, but it carries a long-term risk of skin cancer. Immunosuppressants have not been well assessed in this setting, but methotrexate has been better evaluated than the others.

MeSH terms

  • Acitretin / administration & dosage
  • Acitretin / adverse effects
  • Acitretin / therapeutic use
  • Administration, Topical
  • Anthralin / administration & dosage
  • Anthralin / adverse effects
  • Anthralin / therapeutic use
  • Calcitriol / administration & dosage
  • Calcitriol / adverse effects
  • Calcitriol / analogs & derivatives
  • Calcitriol / therapeutic use
  • Child
  • Cyclosporine / administration & dosage
  • Cyclosporine / adverse effects
  • Cyclosporine / therapeutic use
  • Dermatologic Agents / administration & dosage
  • Dermatologic Agents / adverse effects
  • Dermatologic Agents / therapeutic use
  • Emollients / administration & dosage
  • Emollients / adverse effects
  • Emollients / therapeutic use*
  • Etanercept
  • Humans
  • Immunoglobulin G / administration & dosage
  • Immunoglobulin G / adverse effects
  • Immunoglobulin G / therapeutic use
  • Immunosuppressive Agents / administration & dosage
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use*
  • Methotrexate / administration & dosage
  • Methotrexate / adverse effects
  • Methotrexate / therapeutic use
  • Nicotinic Acids / administration & dosage
  • Nicotinic Acids / adverse effects
  • Nicotinic Acids / therapeutic use
  • Plant Extracts / administration & dosage
  • Plant Extracts / adverse effects
  • Plant Extracts / therapeutic use
  • Psoriasis / drug therapy*
  • Psoriasis / therapy
  • Receptors, Tumor Necrosis Factor / administration & dosage
  • Receptors, Tumor Necrosis Factor / therapeutic use
  • Salicylates / administration & dosage
  • Salicylates / adverse effects
  • Salicylates / therapeutic use
  • Steroids / administration & dosage
  • Steroids / adverse effects
  • Steroids / therapeutic use*
  • Tars / adverse effects
  • Tars / therapeutic use
  • Treatment Outcome
  • Ultraviolet Therapy

Substances

  • Dermatologic Agents
  • Emollients
  • Immunoglobulin G
  • Immunosuppressive Agents
  • Nicotinic Acids
  • Plant Extracts
  • Receptors, Tumor Necrosis Factor
  • Salicylates
  • Steroids
  • Tars
  • calcipotriene
  • juniper tar
  • tazarotene
  • Cyclosporine
  • Calcitriol
  • Acitretin
  • Etanercept
  • Anthralin
  • Methotrexate