Abstract
(1) Plaque psoriasis is the most common form of psoriasis in children. Topical agents should be tried first, especially well-tolerated products such as emollients. Topical corticosteroids are sometimes useful during exacerbations but, given adverse effects, they should only be used for short periods; (2) UVB phototherapy is an option for extensive psoriasis refractory to local treatments, but it carries a long-term risk of skin cancer. Immunosuppressants have not been well assessed in this setting, but methotrexate has been better evaluated than the others.
MeSH terms
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Acitretin / administration & dosage
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Acitretin / adverse effects
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Acitretin / therapeutic use
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Administration, Topical
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Anthralin / administration & dosage
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Anthralin / adverse effects
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Anthralin / therapeutic use
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Calcitriol / administration & dosage
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Calcitriol / adverse effects
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Calcitriol / analogs & derivatives
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Calcitriol / therapeutic use
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Child
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Cyclosporine / administration & dosage
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Cyclosporine / adverse effects
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Cyclosporine / therapeutic use
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Dermatologic Agents / administration & dosage
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Dermatologic Agents / adverse effects
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Dermatologic Agents / therapeutic use
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Emollients / administration & dosage
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Emollients / adverse effects
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Emollients / therapeutic use*
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Etanercept
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Humans
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Immunoglobulin G / administration & dosage
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Immunoglobulin G / adverse effects
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Immunoglobulin G / therapeutic use
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Immunosuppressive Agents / administration & dosage
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Immunosuppressive Agents / adverse effects
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Immunosuppressive Agents / therapeutic use*
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Methotrexate / administration & dosage
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Methotrexate / adverse effects
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Methotrexate / therapeutic use
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Nicotinic Acids / administration & dosage
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Nicotinic Acids / adverse effects
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Nicotinic Acids / therapeutic use
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Plant Extracts / administration & dosage
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Plant Extracts / adverse effects
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Plant Extracts / therapeutic use
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Psoriasis / drug therapy*
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Psoriasis / therapy
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Receptors, Tumor Necrosis Factor / administration & dosage
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Receptors, Tumor Necrosis Factor / therapeutic use
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Salicylates / administration & dosage
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Salicylates / adverse effects
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Salicylates / therapeutic use
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Steroids / administration & dosage
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Steroids / adverse effects
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Steroids / therapeutic use*
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Tars / adverse effects
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Tars / therapeutic use
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Treatment Outcome
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Ultraviolet Therapy
Substances
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Dermatologic Agents
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Emollients
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Immunoglobulin G
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Immunosuppressive Agents
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Nicotinic Acids
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Plant Extracts
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Receptors, Tumor Necrosis Factor
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Salicylates
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Steroids
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Tars
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calcipotriene
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juniper tar
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tazarotene
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Cyclosporine
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Calcitriol
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Acitretin
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Etanercept
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Anthralin
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Methotrexate