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Am J Ind Med. 2010 Mar;53(3):217-23. doi: 10.1002/ajim.20788.

Occupational factors and risk of Parkinson's disease: A population-based case-control study.

Author information

  • 1Department of Neurology, University of Washington, Seattle, USA. jfire@u.washington.edu

Abstract

BACKGROUND:

Parkinson's disease (PD) has been associated with various workplace factors, but the evidence is inconsistent.

OBJECTIVE:

To estimate the risk of PD associated with various jobs and workplace exposures.

METHODS:

We conducted a population-based, case-control study of 404 incident PD cases and 526 age and sex-matched controls, collecting self-reported work histories including job titles and exposures to various industrial toxicants. Relative risks of PD from these exposures were estimated with odds ratios (OR) and 95% confidence intervals (CI) using logistic regression.

RESULTS:

Risk was not significantly affected by farming work, by metal work, or by exposure to pesticides, metals, or solvents.

CONCLUSIONS:

These findings do not provide support for the hypothesis that workplace factors affect the risk of PD.

2009 Wiley-Liss, Inc.

PMID:
20025075
[PubMed - indexed for MEDLINE]
PMCID:
PMC3299410
Free PMC Article
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