Steric effects direct the binding of porphyrins to tetramolecular quadruplex DNA

Chem Commun (Camb). 2009 Dec 21:(47):7393-5. doi: 10.1039/b919273e. Epub 2009 Nov 3.

Abstract

The binding motifs of copper(II) porphyrins with G quadruplex DNA structures vary markedly depending on the steric demands of the ligand and the host structure.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Circular Dichroism
  • Copper / chemistry
  • G-Quadruplexes*
  • Ligands
  • Porphyrins / chemistry*
  • Zinc / chemistry

Substances

  • Ligands
  • Porphyrins
  • Copper
  • Zinc