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Kidney Blood Press Res. 2009;32(6):451-6. doi: 10.1159/000266480. Epub 2009 Dec 17.

Peritoneal dialysis and hemodialysis in systemic lupus erythematosus patients: comparison of clinical outcomes.

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  • 1Department of Nephrology, Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Taoyuan, Taiwan, ROC.

Abstract

BACKGROUND:

This study compared peritoneal dialysis (PD) and hemodialysis (HD) outcomes between female systemic lupus erythematosus (SLE) patients with end-stage renal disease (ESRD) due to lupus nephropathy.

METHODS:

22 female SLE patients undergoing PD were compared with 14 female SLE patients receiving HD. Clinical outcomes and infective complications were reviewed.

RESULTS:

The overall mortality rate was much higher in the PD group (6/22) than in the HD group (1/14) (p = 0.027). PD patients had higher C-reactive protein level (37.1 +/- 41.4 vs. 6.7 +/- 9.5 mg/l, p = 0.037) and numbers of infectious episode (PD vs. HD: 1 episode per 33.16 patient-months vs. 1 episode per 118.26 patient-months, respectively, p = 0.046). Before the end of the observation period, HD patients had higher serum albumin (3.8 +/- 0.2 vs. 3.3 +/- 0.6 g/dl, p = 0.01).

CONCLUSIONS:

In female SLE patients with ESRD due to lupus nephropathy, clinical outcomes are better after undergoing HD than after undergoing PD.

Copyright 2009 S. Karger AG, Basel.

PMID:
20016213
[PubMed - indexed for MEDLINE]
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