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Kidney Blood Press Res. 2009;32(6):451-6. doi: 10.1159/000266480. Epub 2009 Dec 17.

Peritoneal dialysis and hemodialysis in systemic lupus erythematosus patients: comparison of clinical outcomes.

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  • 1Department of Nephrology, Chang Gung Memorial Hospital and Chang Gung University, College of Medicine, Taoyuan, Taiwan, ROC.



This study compared peritoneal dialysis (PD) and hemodialysis (HD) outcomes between female systemic lupus erythematosus (SLE) patients with end-stage renal disease (ESRD) due to lupus nephropathy.


22 female SLE patients undergoing PD were compared with 14 female SLE patients receiving HD. Clinical outcomes and infective complications were reviewed.


The overall mortality rate was much higher in the PD group (6/22) than in the HD group (1/14) (p = 0.027). PD patients had higher C-reactive protein level (37.1 +/- 41.4 vs. 6.7 +/- 9.5 mg/l, p = 0.037) and numbers of infectious episode (PD vs. HD: 1 episode per 33.16 patient-months vs. 1 episode per 118.26 patient-months, respectively, p = 0.046). Before the end of the observation period, HD patients had higher serum albumin (3.8 +/- 0.2 vs. 3.3 +/- 0.6 g/dl, p = 0.01).


In female SLE patients with ESRD due to lupus nephropathy, clinical outcomes are better after undergoing HD than after undergoing PD.

Copyright 2009 S. Karger AG, Basel.

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