The enigmatic roles of microglial versus neuronal progranulin in neurological disease

Acta Neuropathol. 2010 Jan;119(1):107-9. doi: 10.1007/s00401-009-0623-z. Epub 2009 Dec 12.

Author

Jason L Eriksen¹

Affiliation

¹ Pharmacological and Pharmaceutical Science, University of Houston, Houston, TX 77204, USA. jeriksen@central.uh.edu

PMID: 20012633
DOI: 10.1007/s00401-009-0623-z

No abstract available

Publication types

Comment

MeSH terms

Animals
Brain / metabolism
Frontotemporal Lobar Degeneration / genetics
Frontotemporal Lobar Degeneration / metabolism*
Granulins
Humans
Intercellular Signaling Peptides and Proteins / genetics
Intercellular Signaling Peptides and Proteins / metabolism*
Macrophages / metabolism
Mice
Microglia / metabolism*
Mutation
Neurons / metabolism*
Progranulins
Spinal Cord / metabolism
Spinal Cord Injuries / genetics
Spinal Cord Injuries / metabolism*

Substances

GRN protein, human
Granulins
Grn protein, mouse
Intercellular Signaling Peptides and Proteins
Progranulins