Brucine-derived amino alcohol catalyzed asymmetric Henry reaction: an orthogonal enantioselectivity approach

Hun Young Kim; Kyungsoo Oh

doi:10.1021/ol902380z

Brucine-derived amino alcohol catalyzed asymmetric Henry reaction: an orthogonal enantioselectivity approach

Org Lett. 2009 Dec 17;11(24):5682-5. doi: 10.1021/ol902380z.

Authors

Hun Young Kim¹, Kyungsoo Oh

Affiliation

¹ Department of Chemistry and Chemical Biology, Indiana University Purdue University Indianapolis (IUPUI), Indianapolis, Indiana 46202, USA.

PMID: 20000444
DOI: 10.1021/ol902380z

Abstract

A new approach to both enantioenriched Henry products is developed by use of different molecularities of metal-ligand complexes generated from Cu(I) and Zn(II) metals with readily available chiral amino alcohol 1.