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Int Urogynecol J. 2010 Apr;21(4):467-73. doi: 10.1007/s00192-009-1061-0. Epub 2009 Dec 9.

Long-term results of vaginal repairs with and without xenograft reinforcement.

Author information

  • 1Department of Gynecology and Obstetrics, Herlev Hospital, University of Copenhagen, 2730 Herlev, Copenhagen, Denmark. lonemouritsen@newmail.dk

Abstract

INTRODUCTION AND HYPOTHESIS:

The aim of this paper is to study if xenograft reinforcement of vaginal repair reduces recurrence of prolapse.

METHODS:

Results 1-5 years after vaginal repair were studied in 41 cases with xenograft and in 82 matched controls without. Symptoms were evaluated by a validated questionnaire and anatomy by pelvic organ prolapse quantification (POPQ).

RESULTS:

Significant more cases, 97% versus 81% controls, felt cured or much improved (p = 0.02); 11% of cases and 19% of controls had POP symptoms, POPQ > -1 was found in 31% cases and 24% controls. Defining recurrence as POPQ > -1 plus symptoms revealed recurrence in 3% of cases and 12% controls. None of the recurrence rates was significantly different for cases versus controls. No vaginal erosions were seen. Previous surgery was a significant risk factor with odds ratio 7.3 for another recurrence.

CONCLUSIONS:

Recurrence rates defined by POPQ plus symptoms were low compared to literature. Xenograft reinforcement might improve results.

PMID:
19998024
[PubMed - indexed for MEDLINE]
PMCID:
PMC2977064
Free PMC Article
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