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Opt Express. 2009 Nov 9;17(23):20700-6. doi: 10.1364/OE.17.020700.

All-fiber CARS microscopy of live cells.

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  • 1Department of Physics, Queen's University, Kingston, Ontario, K7L 3N6, Canada.


Using an all-fiber laser system consisting of a femtosecond Er/Yb fiber oscillator as the pump and an ultra-highly nonlinear fiber for Stokes generation, we demonstrate multimodal (TPF+SHG+CARS) non-linear optical microscopy of both tissue samples and live cells. Multimodal imaging was successfully performed with pixel dwell times as short as 4 micros at low laser powers (< 40 mW total).

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