J Nerv Ment Dis. 2009 Nov;197(11):865-8.

A preliminary controlled trial of cognitive behavioral therapy in clozapine-resistant schizophrenia.

Barretto EM, Kayo M, Avrichir BS, Sa AR, Camargo MG, Napolitano IC, Nery FG, Pinto JA Jr, Bannwart S, Scemes S, Di Sarno E, Elkis H.

Source

Department and Institute of Psychiatry, University of São Paulo Medical School, São Paulo, SP-05403-010, Brazil.

Abstract

The use of cognitive-behavior therapy (CBT) in addition to antipsychotic regimen to treat persistent psychotic symptoms of schizophrenia is growing. The aim of this study was to compare the efficacy of CBT to a befriending (BF) control group in patients with schizophrenia who are refractory to clozapine. Twenty-one patients completed the 21-week trial. In comparison with the control group, the CBT group showed a significant improvement in the General Psychopathology and total score of the Positive and Negative Syndrome Scale, as well as an improvement of Quality of Life scale. The improvement in psychopathology persisted at 6-month follow-up assessment.

PMID:: 19996727; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Clozapine

LinkOut - more resources

Full Text Sources

Medical

Schizophrenia - MedlinePlus Health Information

Molecular Biology Databases

CLOZAPINE - HSDB

Supplemental Content

Save items

Related citations in PubMed

A randomized controlled trial of cognitive-behavioral therapy for persistent symptoms in schizophrenia resistant to medication. [Arch Gen Psychiatry. 2000]
A randomized controlled trial of cognitive-behavioral therapy for persistent symptoms in schizophrenia resistant to medication.
Sensky T, Turkington D, Kingdon D, Scott JL, Scott J, Siddle R, O'Carroll M, Barnes TR. Arch Gen Psychiatry. 2000 Feb; 57(2):165-72.
A randomized controlled trial of cognitive-behavior therapy for persistent symptoms in schizophrenia: a five-year follow-up. [Schizophr Res. 2008]
A randomized controlled trial of cognitive-behavior therapy for persistent symptoms in schizophrenia: a five-year follow-up.
Turkington D, Sensky T, Scott J, Barnes TR, Nur U, Siddle R, Hammond K, Samarasekara N, Kingdon D. Schizophr Res. 2008 Jan; 98(1-3):1-7. Epub 2007 Oct 23.
Cognitive-behavioural therapy for refractory psychotic symptoms of schizophrenia resistant to atypical antipsychotic medication. Randomised controlled trial. [Br J Psychiatry. 2005]
Cognitive-behavioural therapy for refractory psychotic symptoms of schizophrenia resistant to atypical antipsychotic medication. Randomised controlled trial.
Valmaggia LR, van der Gaag M, Tarrier N, Pijnenborg M, Slooff CJ. Br J Psychiatry. 2005 Apr; 186:324-30.
Review [Psychopharmacological treatment of treatment-resistant schizophrenia]. [Ugeskr Laeger. 1997]
Review [Psychopharmacological treatment of treatment-resistant schizophrenia].
Lublin HK. Ugeskr Laeger. 1997 Nov 24; 159(48):7128-33.
Review Cognitive behavioral therapy for schizophrenia: an empirical review. [J Nerv Ment Dis. 2001]
Review Cognitive behavioral therapy for schizophrenia: an empirical review.
Rector NA, Beck AT. J Nerv Ment Dis. 2001 May; 189(5):278-87.

See reviews... See all...

Cited by 1 PubMed Central article

Pharmacotherapy for treatment-resistant schizophrenia. [Neuropsychiatr Dis Treat. 2011]
Pharmacotherapy for treatment-resistant schizophrenia.
McIlwain ME, Harrison J, Wheeler AJ, Russell BR. Neuropsychiatr Dis Treat. 2011; 7:135-49. Epub 2011 Mar 17.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

A preliminary controlled trial of cognitive behavioral therapy in clozapine-resi...
A preliminary controlled trial of cognitive behavioral therapy in clozapine-resistant schizophrenia.
J Nerv Ment Dis. 2009 Nov ;197(11):865-8.

PubMed
Attachment of bacteria to tonsillar epithelium during acute tonsillitis.
Attachment of bacteria to tonsillar epithelium during acute tonsillitis.
J Laryngol Otol. 1991 Jan ;105(1):29-32.

PubMed
Association between bone mineral density and metabolic syndrome in postmenopausa...
Association between bone mineral density and metabolic syndrome in postmenopausal Korean women.
Gynecol Obstet Invest. 2010 ;69(3):145-52. Epub 2009 Dec 7 .

PubMed
Long-term consequences of childhood ADHD on criminal activities.
Long-term consequences of childhood ADHD on criminal activities.
J Ment Health Policy Econ. 2009 Sep ;12(3):119-38.

PubMed
Relationship of primary care physicians' patient caseload with measurement of qu...
Relationship of primary care physicians' patient caseload with measurement of quality and cost performance.
JAMA. 2009 Dec 9 ;302(22):2444-50.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: