The isolation of cDNA clones for CD48. [Immunogenetics. 1991]

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1: Immunogenetics. 1991;33(2):113-7.Links

The isolation of cDNA clones for CD48.

Vaughan HA, Henning MM, Purcell DF, McKenzie IF, Sandrin MS.

Department of Pathology, University of Melbourne, Parkville, Victoria, Australia.

HuLy-m3 is an Mr 47,000 pan-leukocyte antigen detected by the monoclonal antibody (mAb) 5-4.8. This report describes the isolation and analysis of a cDNA clone encoding HuLy-m3. Serological analysis demonstrated that antibodies of the CD48 cluster also reacted with transfected cells expressing HuLy-m3. The DNA sequence of the clone suggests linkage to the cell membrane through a glycosyl phosphatidylinositol tail and this was verified experimentally. Sequence similarity with the human B-cell activation antigen Blast-1 was noted.

PMID: 1999351 [PubMed - indexed for MEDLINE]

The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1.
Immunogenetics. 1991; 33(2):108-12.

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Cited by 4 PubMed Central articles

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