Tidsskr Nor Laegeforen. 1991 Jan 20;111(2):193-5.

[Dependence on carisoprodol (Somadril)? A prospective withdrawal study among prisoners].

[Article in Norwegian]

Source

Helsetjenesten ved Ila landsfengsel og sikringsanstalt, Oslo.

Abstract

Carisoprodol (Somadril) was gradually withdrawn for a fortnight in nine male prisoners who had been taking daily doses of from 700 to 2,100 mg for at least nine months. The patients were assessed clinically during the withdrawal period, with special attention to the occurrence of abstinence symptoms. Most of the patients reported mental distress, such as anxiety, insomnia and irritability. Cranial and muscular pain and vegetative symptoms were also frequently reported. Most of these symptoms were transient, and no seizures or psychotic reactions occurred. Our information from drug addicts indicates that carisoprodol can be misused as a narcotic. The occurrence of abstinence symptoms during withdrawal supports this supposition. We propose a more gradual reduction of the doses when terminating medication with carisoprodol in general practice.

PMID:: 1998178; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

English Abstract

MeSH Terms

Substances

Carisoprodol

LinkOut - more resources

Molecular Biology Databases

CARISOPRODOL - HSDB

Supplemental Content

Related citations

Is the frequency of carisoprodol withdrawal syndrome increasing? [Pharmacotherapy. 2007]
Is the frequency of carisoprodol withdrawal syndrome increasing?
Reeves RR, Hammer JS, Pendarvis RO. Pharmacotherapy. 2007 Oct; 27(10):1462-6.
Carisoprodol withdrawal syndrome. [Pharmacotherapy. 2004]
Carisoprodol withdrawal syndrome.
Reeves RR, Beddingfield JJ, Mack JE. Pharmacotherapy. 2004 Dec; 24(12):1804-6.
Treatment of carisoprodol dependence: a case report. [J Psychiatr Pract. 2005]
Treatment of carisoprodol dependence: a case report.
Rohatgi G, Rissmiller DJ, Gorman JM. J Psychiatr Pract. 2005 Sep; 11(5):347-52.
Review Carisoprodol: abuse potential and withdrawal syndrome. [Curr Drug Abuse Rev. 2010]
Review Carisoprodol: abuse potential and withdrawal syndrome.
Reeves RR, Burke RS. Curr Drug Abuse Rev. 2010 Mar; 3(1):33-8.
Review Carisoprodol (Soma): a new and cautious perspective on an old agent. [South Med J. 1993]
Review Carisoprodol (Soma): a new and cautious perspective on an old agent.
Littrell RA, Hayes LR, Stillner V. South Med J. 1993 Jul; 86(7):753-6.

See reviews... See all...

Cited by 1 PubMed Central article

Carisoprodol use and abuse in Norway: a pharmacoepidemiological study. [Br J Clin Pharmacol. 2007]
Carisoprodol use and abuse in Norway: a pharmacoepidemiological study.
Bramness JG, Furu K, Engeland A, Skurtveit S. Br J Clin Pharmacol. 2007 Aug; 64(2):210-8. Epub 2007 Feb 12.

Chemical compound information

Carisoprodol

MW: 260.32 g/mol

MF: C₁₂H₂₄N₂O₄

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

[Dependence on carisoprodol (Somadril)? A prospective withdrawal study among pri...
[Dependence on carisoprodol (Somadril)? A prospective withdrawal study among prisoners].
Tidsskr Nor Laegeforen. 1991 Jan 20 ;111(2):193-5.

PubMed
Arthrographically guided splint therapy for recapturing the temporomandibular jo...
Arthrographically guided splint therapy for recapturing the temporomandibular joint meniscus.
Oral Surg Oral Med Oral Pathol. 1984 Mar ;57(3):235-40.

PubMed
Use of an implant for intraosseous infusion as supportive therapy for a Vietname...
Use of an implant for intraosseous infusion as supportive therapy for a Vietnamese pot-bellied pig with urethral obstruction caused by a polyp.
J Am Vet Med Assoc. 1992 Nov 15 ;201(10):1587-90.

PubMed
Orientation-sella-nasion or Frankfort horizontal.
Orientation-sella-nasion or Frankfort horizontal.
Am J Orthod. 1976 Jun ;69(6):648-54.

PubMed
Effect of spectacle correction on the progression of myopia in children--a liter...
Effect of spectacle correction on the progression of myopia in children--a literature review.
J Am Optom Assoc. 1994 Feb ;65(2):117-28.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: