Format

Send to

Choose Destination
See comment in PubMed Commons below
J Biotechnol. 2010 Feb 1;145(3):240-3. doi: 10.1016/j.jbiotec.2009.11.022. Epub 2009 Dec 4.

Hydrolase-catalyzed fast Henry reaction of nitroalkanes and aldehydes in organic media.

Author information

  • 1Department of Chemistry, Zhejiang University, Hangzhou 310027, Zhejiang, PR China.

Abstract

Nitroalkanes underwent fast additions to a variety of structurally diverse aldehydes under the catalysis of d-aminoacylase in DMSO. The influences of reaction conditions including solvents, temperature, enzyme concentration and molar ratio of substrates were systematically investigated. Seventeen products were obtained in short time with moderate to high yields. It is the first report on hydrolase-catalyzed fast Henry reaction in organic solvent.

Copyright 2009 Elsevier B.V. All rights reserved.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk