We present two cases of obstructive sleep apnea (OSA) in which one of the subjects was managed with virtual scanning, which is a computer interactive diagnostic and therapeutic technology, and the other was treated with nutrition. We propose an oxidative stress concept as the biochemical basis of the two management options. It is important to consider the validity of virtual scanning Technology (which can be used to manage sleep apnea noninvasively) and to determine whether oxidative stress is the biochemical basis for this technology. It will be beneficial to develop a framework for integration into clinical practice.