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J Bacteriol. 2010 Feb;192(3):888-92. doi: 10.1128/JB.01255-09. Epub 2009 Nov 30.

Genome sequence of a recently emerged, highly transmissible, multi-antibiotic- and antiseptic-resistant variant of methicillin-resistant Staphylococcus aureus, sequence type 239 (TW).

Author information

  • 1The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, United Kingdom. mh3@sanger.ac.uk

Abstract

The 3.1-Mb genome of an outbreak methicillin-resistant Staphylococcus aureus (MRSA) strain (TW20) contains evidence of recently acquired DNA, including two large regions (635 kb and 127 kb). The strain is resistant to a wide range of antibiotics, antiseptics, and heavy metals due to resistance genes encoded on mobile genetic elements and also mutations in housekeeping genes.

PMID:
19948800
[PubMed - indexed for MEDLINE]
PMCID:
PMC2812470
Free PMC Article
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