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Cell. 2009 Nov 25;139(5):861-3. doi: 10.1016/j.cell.2009.11.013.

Pushing and pulling: microtubules mediate meiotic pairing and synapsis.

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  • 1Stowers Institute for Medical Research, Kansas City, MO, USA.


Meiotic pairing in the nematode Caenorhabditis elegans is facilitated by chromosomal sites known as pairing centers that are tethered to the nuclear envelope. Sato et al. (2009) and Penkner et al. (2009) provide insight into how proteins linking pairing centers and the microtubule cytoskeleton mediate homolog pairing and restrict synapsis to homologous pairs of chromosomes.

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