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AJNR Am J Neuroradiol. 2010 Jun;31(6):1100-2. doi: 10.3174/ajnr.A1863. Epub 2009 Nov 26.

Diffusion-weighted imaging in fetuses with unilateral cortical malformations and callosal agenesis.

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  • 1Department of Radiology and Biomedical Imaging, University of California-San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA. Orit.Glenn@radiology.ucsf.edu


DWI was performed in fetuses with callosal agenesis and unilateral cortical malformations. ADC values were retrospectively measured in the developing white matter underlying the cortical malformation and compared with the corresponding contralateral white matter. In all 3 patients, ADC values were lower under the areas of cortical malformation compared with the normal contralateral side. Our findings suggest that there are structural differences in the developing white matter underlying areas of cortical malformation.

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