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AIDS Rev. 2009 Oct-Dec;11(4):190-204.

Liver and kidney transplantation in HIV-infected patients.

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  • 1Department of Surgery, University of California, San Francisco, CA, USA.

Abstract

HIV infection has evolved into a chronic condition as a result of improvements in therapeutic options. Chronic exposure with HIV and associated co-pathogens as well as toxicities from prolonged therapy with antiviral medications has resulted in increased morbidity and mortality rates from end-stage liver and kidney disease in the HIV-infected population. Since the definitive treatment for end-stage organ failure is transplantation, demand has increased among HIV-infected patients. Although the transplant community has been slow to recognize HIV as a chronic condition, many transplant centers have eliminated HIV infection as a contraindication to transplantation as a result of better patient management and demand. This review examines the current clinical strategies and issues surrounding liver and kidney transplantation in HIV-infected patients.

PMID:
19940946
[PubMed - indexed for MEDLINE]
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