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J Bacteriol. 2010 Feb;192(3):896-900. doi: 10.1128/JB.01122-09. Epub 2009 Nov 20.

Characterization of the CtsR stress response regulon in Lactobacillus plantarum.

Author information

  • 1Department of Biomedical Sciences, University of Foggia, Viale L. Pinto, 71100 Foggia, Italy.

Abstract

Lactobacillus plantarum ctsR was characterized. ctsR was found to be cotranscribed with clpC and induced in response to various abiotic stresses. ctsR deletion conferred a heat-sensitive phenotype with peculiar cell morphological features. The transcriptional pattern of putative CtsR regulon genes was examined in the Delta ctsR mutant. Direct CtsR-dependent regulation was demonstrated by DNA-binding assays using recombinant CtsR and the promoters of the ctsR-clpC operon and hsp1.

PMID:
19933364
[PubMed - indexed for MEDLINE]
PMCID:
PMC2812460
Free PMC Article

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