Cancer Genet Cytogenet. 1991 Feb;51(2):195-205.

Trisomy 8 as a nonrandom secondary change in myxoid liposarcoma.

Sreekantaiah C, Karakousis CP, Leong SP, Sandberg AA.

Source

Cancer Center of Southwest Biomedical Research Institute of Genetrix, Scottsdale, Arizona 85251.

Abstract

We report the cytogenetic findings in 5 cases of myxoid liposarcoma following short-term culture. In all 5 tumors a t(12:16)(q13:p11), characteristic of the myxoid form of liposarcoma, was observed. Trisomy 8 was present in two tumors as the only additional change and in a third in addition to other abnormalities. In the other two tumors the t(12:16) was present as the sole change. Three other myxoid liposarcomas with trisomy 8 as an additional aberration have been reported, suggesting that it could represent a non-random secondary event in these tumors.

PMID:: 1993305; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Grant Support

Publication Types

MeSH Terms

Grant Support

CA-41183/CA/NCI NIH HHS/United States

LinkOut - more resources

Full Text Sources

Elsevier Science

Other Literature Sources

COS Scholar Universe

Supplemental Content

Save items

Related citations in PubMed

Chromosome abnormalities in liposarcomas. [Cancer Genet Cytogenet. 1992]
Chromosome abnormalities in liposarcomas.
Ohjimi Y, Iwasaki H, Kaneko Y, Ishiguro M, Ohgami A, Fujita C, Shinohara N, Yoshitake K, Kikuchi M. Cancer Genet Cytogenet. 1992 Dec; 64(2):111-7.
Deletion 6q in three cases of mixed-type liposarcoma in addition to t(12;16)(q13;p11) [Cancer Genet Cytogenet. 1995]
Deletion 6q in three cases of mixed-type liposarcoma in addition to t(12;16)(q13;p11)
Altungoz O, Meloni AM, Peier A, Zalupski M, Spanier S, Brooks JS, Sandberg AA. Cancer Genet Cytogenet. 1995 Feb; 79(2):104-10.
Cytogenetic studies of adipose tissue tumors. II. Recurrent reciprocal translocation t(12;16)(q13;p11) in myxoid liposarcomas. [Cancer Genet Cytogenet. 1986]
Cytogenetic studies of adipose tissue tumors. II. Recurrent reciprocal translocation t(12;16)(q13;p11) in myxoid liposarcomas.
Turc-Carel C, Limon J, Dal Cin P, Rao U, Karakousis C, Sandberg AA. Cancer Genet Cytogenet. 1986 Dec; 23(4):291-9.
Review Chromosomal evolution and tumor progression in a myxoid liposarcoma. [Acta Orthop Scand. 1990]
Review Chromosomal evolution and tumor progression in a myxoid liposarcoma.
Orndal C, Mandahl N, Rydholm A, Nilbert M, Heim S, Akerman M, Mitelman F. Acta Orthop Scand. 1990 Apr; 61(2):99-105.
Review Translocation t(12;22)(q13;q12.2-12.3) in a clear cell sarcoma of tendons and aponeuroses. [Genes Chromosomes Cancer. 1993]
Review Translocation t(12;22)(q13;q12.2-12.3) in a clear cell sarcoma of tendons and aponeuroses.
Mrózek K, Karakousis CP, Perez-Mesa C, Bloomfield CD. Genes Chromosomes Cancer. 1993 Apr; 6(4):249-52.

See reviews... See all...

Cited by 4 PubMed Central articles

Cytogenetics and molecular genetics of myxoid soft-tissue sarcomas. [Genet Res Int. 2011]
Cytogenetics and molecular genetics of myxoid soft-tissue sarcomas.
Nishio J, Iwasaki H, Nabeshima K, Naito M. Genet Res Int. 2011; 2011:497148. Epub 2011 Jul 28.
Liposarcoma: molecular genetics and therapeutics. [Sarcoma. 2011]
Liposarcoma: molecular genetics and therapeutics.
Conyers R, Young S, Thomas DM. Sarcoma. 2011; 2011:483154. Epub 2010 Dec 27.
Review Chromosomal aberrations in soft tissue tumors. Relevance to diagnosis, classification, and molecular mechanisms. [Am J Pathol. 1994]
Review Chromosomal aberrations in soft tissue tumors. Relevance to diagnosis, classification, and molecular mechanisms.
Sreekantaiah C, Ladanyi M, Rodriguez E, Chaganti RS. Am J Pathol. 1994 Jun; 144(6):1121-34.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Trisomy 8 as a nonrandom secondary change in myxoid liposarcoma.
Trisomy 8 as a nonrandom secondary change in myxoid liposarcoma.
Cancer Genet Cytogenet. 1991 Feb ;51(2):195-205.

PubMed
Doxorubicin and cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fl...
Doxorubicin and cyclophosphamide versus cyclophosphamide, methotrexate, and 5-fluorouracil as adjuvant chemotherapy in breast cancer.
J Chemother. 2009 Nov ;21(5):558-65.

PubMed
Green tea, black tea, and epigallocatechin modify body composition, improve gluc...
Green tea, black tea, and epigallocatechin modify body composition, improve glucose tolerance, and differentially alter metabolic gene expression in rats fed a high-fat diet.
Nutr Res. 2009 Nov ;29(11):784-93.

PubMed
Low vision among preschool children in the Beijing Study of Visual Impairment.
Low vision among preschool children in the Beijing Study of Visual Impairment.
Am J Ophthalmol. 2009 Dec ;148(6):953-4; author reply 954.

PubMed
MMP-12 catalytic domain recognizes and cleaves at multiple sites in human skin c...
MMP-12 catalytic domain recognizes and cleaves at multiple sites in human skin collagen type I and type III.
Biochim Biophys Acta. 2010 Apr ;1804(4):731-9. Epub 2009 Nov 22 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: