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Eur J Radiol. 2011 Jul;79(1):92-5. doi: 10.1016/j.ejrad.2009.10.025. Epub 2009 Nov 18.

Gray matter abnormalities in Internet addiction: a voxel-based morphometry study.

Author information

  • 1Department of Radiology, RenJi Hospital, Jiao Tong University Medical School, Shanghai 200127, PR China. clare1475@hotmail.com

Abstract

BACKGROUND:

This study aims to investigate brain gray matter density (GMD) changes in adolescents with Internet addiction (IA) using voxel-based morphometry (VBM) analysis on high-resolution T1-weighted structural magnetic resonance images.

METHODS:

Eighteen IA adolescents and 15 age- and gender-matched healthy controls took part in this study. High-resolution T1-weighted magnetic resonance imaging scans were performed on the two groups. VBM analysis was used to compare the GMD between the two groups.

RESULTS:

Compared with healthy controls, IA adolescents had lower GMD in the left anterior cingulate cortex, left posterior cingulate cortex, left insula, and left lingual gyrus.

CONCLUSIONS:

Our findings suggested that brain structural changes were present in IA adolescents, and this finding may provide a new insight into the pathogenesis of IA.

Copyright © 2009 Elsevier Ireland Ltd. All rights reserved.

PMID:
19926237
[PubMed - indexed for MEDLINE]
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