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Clin Chest Med. 2009 Dec;30(4):783-96, x. doi: 10.1016/j.ccm.2009.08.008.

Biomarkers of disease activity, cure, and relapse in tuberculosis.

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  • 1Department of Infectious Disease Immunology, Statens Serum Institute, Artillerivej 5, 2300 KĂžbenhavn S, Denmark.


The changing face of tuberculosis, with epidemics fueled by HIV and urbanization in much of the world and a relative increase in the importance of latent tuberculosis as a source of cases in the more economically developed countries, has led to a demand for more robust, clinically applicable diagnostic tools. As a result, research aiming to identify biomarkers of Mycobacterium tuberculosis infection and disease has flourished. This article discusses the most recent findings of that work.

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