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    Cases J. 2009 Sep 14;2:7456.

    Extramedullary relapse of IgA-lambda myeloma after recent bortezomib therapy: a case report.

    Waterhouse DF, Moloney GA, Gargoum FS, Hayden PS, O'Gorman T.

    Source

    Department of Gastroenterology, University College Hospital, Galway, Ireland. deirdrewaterhouse@ireland.com

    Abstract

    Intracranial plasmacytomas are an uncommon presentation of extramedullary relapse of multiple myeloma. The optimal management of extramedullary plasmacytomas remains unclear, with initial reports of bortezomib showing promising clinical results. We describe a case of multiple extracellular, including intracranial, plasmacytoma, with no evidence of marrow involvement, in a patient with relapsed IgA multiple myeloma. To our knowledge, this is the first reported case of a patient with rapid extramedullary relapse of disease despite recent exposure to bortezomib and dexamethasone.

    PMID:
    19918466
    [PubMed]
    PMCID:
    PMC2769356
    Free PMC Article

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