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J Urol. 2010 Jan;183(1):21-6. doi: 10.1016/j.juro.2009.09.030.

The impact of male circumcision on HIV transmission.

Author information

  • 1Department of Urology, Philip R Lee Institute for Health Policy Studies, University of California, Berkeley, Berkeley, California 94143-1695, USA.

Abstract

PURPOSE:

Adult male circumcision is currently being implemented as an HIV prevention strategy worldwide. We reviewed the literature on adult male circumcision in the prevention of HIV.

MATERIALS AND METHODS:

A MEDLINE search was used to identify current literature addressing HIV and male circumcision. The data from that literature were reviewed and summarized.

RESULTS:

Three randomized, controlled trials demonstrate that circumcising adult males reduces the incidence of HIV by 50% to 60%. Adult male circumcision does not seem to have an adverse impact on sexual function. Epidemiological and economic modeling suggests that adult male circumcision can potentially be a highly cost-effective strategy for HIV prevention.

CONCLUSIONS:

Safe, high quality, low cost adult male circumcision services should be made available to regions with a high HIV incidence as part of a comprehensive HIV prevention package.

PMID:
19913816
[PubMed - indexed for MEDLINE]
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