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Acta Paediatr. 2010 Nov;99(11):1661-5. doi: 10.1111/j.1651-2227.2009.01596.x.

Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge?

Author information

  • 1Department of Paediatrics, Oslo University Hospital, Oslo, Norway. kjersti.ramstad@rikshospitalet.no

Abstract

AIM:

The aim of the study was to explore the timing of effects of intrathecal baclofen therapy in children with cerebral palsy.

METHODS:

Thirty five children with severe disabilities with cerebral palsy who started continuous intrathecal baclofen therapy (CITB) were followed for 18 months. Pain, number of awakenings during night, spasticity, GMFM-66 scores and PEDI scores were recorded the day before pump implantation and after 6 and 18 months of treatment respectively.

RESULTS:

Introduction of CITB was associated with changes across all ICF dimensions. Reduced pain and improved sleep occurred within 6 months of treatment. Social function improved within 6 months and continued to improve until 18 months of CITB. Mobility also improved, but with a latency.

CONCLUSION:

There seems to be a sequence of changes after introduction of continuous intrathecal baclofen in a child with cerebral palsy that may guide the multidisciplinary team in their timing of therapy during post-surgical follow-up.

© 2009 The Author(s)/Journal Compilation © 2009 Foundation Acta Paediatrica.

PMID:
19912148
[PubMed - indexed for MEDLINE]
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