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Nutr Rev. 2009 Nov;67(11):624-31. doi: 10.1111/j.1753-4887.2009.00230.x.

Beta-glucans in higher fungi and their health effects.

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  • 1Department of Food Engineering, Faculty of Technology, Tomas Bata University in Zlin, 762 72 Zlin, Czech Republic. rop@ft.utb.cz

Abstract

Together with chitin, the beta-glucans are components of mycetes' cell walls. A high level of biological efficiency has been found in beta-glucans, especially beta-1,3-D-glucans and beta-1,6-D-glucans isolated from some basidiomycetes. (Biological efficiency refers to the relative ability of beta-glucans to promote a desired response, for example to induce leukocyte activation and to produce inflammatory mediators.) These polysaccharides increase the number of Th1 lymphocytes, which help protect organisms against allergic reactions. A number of beta-glucans, for example pleuran from Oyster (Pleurotus spp.) mushrooms or lentinan from Shiitake (Lentinus edodes) mushrooms, have shown marked anticarcinogenic activity. In addition to having an immunity-stimulating effect, beta-glucans may participate in physiological processes related to the metabolism of fats in the human body. Their application results in a decrease in the total cholesterol content in blood and may also contribute to reductions in body weight.

PMID:
19906249
[PubMed - indexed for MEDLINE]
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