Display Settings:

Format

Send to:

Choose Destination
Oncologist. 2009 Nov;14(11):1070-82. doi: 10.1634/theoncologist.2009-0094. Epub 2009 Nov 6.

Circulating tumor cells: evolving evidence and future challenges.

Author information

  • 1Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.

Abstract

Circulating tumor cells (CTCs) are rare malignant cells found in the peripheral blood that originate from the primary tumor or metastatic sites. New techniques have been developed to isolate and characterize these cells. CTC enumeration has been incorporated into different fields of oncology as a prognostic marker, a tool to monitor therapy response, and a method to understand basic tumor characteristics. This review covers the different techniques available for isolation of CTCs, the clinical utility of CTCs in breast, prostate, and colon cancer, and future directions in this field.

PMID:
19897536
[PubMed - indexed for MEDLINE]
Free full text

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk