Comment on "Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression"

J Immunol. 2009 Nov 15;183(10):6040. doi: 10.4049/jimmunol.0990093.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Animals
  • CD8-Positive T-Lymphocytes / drug effects
  • CD8-Positive T-Lymphocytes / immunology*
  • Cytotoxicity, Immunologic* / drug effects
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Immunotherapy
  • Indoleamine-Pyrrole 2,3,-Dioxygenase / antagonists & inhibitors
  • Indoleamine-Pyrrole 2,3,-Dioxygenase / metabolism*
  • Neoplasms / enzymology
  • Neoplasms / immunology
  • Neoplasms / therapy*
  • Rats
  • Tryptophan / analogs & derivatives
  • Tryptophan / pharmacology

Substances

  • Enzyme Inhibitors
  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • tryptophan methyl ester
  • Tryptophan