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Dynamic and redundant regulation of LRRK2 and LRRK1 expression.
Biskup S, Moore DJ, Rea A, Lorenz-Deperieux B, Coombes CE, Dawson VL, Dawson TM, West AB. Biskup S, et al. BMC Neurosci. 2007 Nov 28;8:102. doi: 10.1186/1471-2202-8-102. BMC Neurosci. 2007. PMID: 18045479 Free PMC article.
A comparative study of Lrrk2 function in primary neuronal cultures.
Dächsel JC, Behrouz B, Yue M, Beevers JE, Melrose HL, Farrer MJ. Dächsel JC, et al. Parkinsonism Relat Disord. 2010 Dec;16(10):650-5. doi: 10.1016/j.parkreldis.2010.08.018. Epub 2010 Sep 17. Parkinsonism Relat Disord. 2010. PMID: 20850369 Free PMC article.
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice.
Herzig MC, Kolly C, Persohn E, Theil D, Schweizer T, Hafner T, Stemmelen C, Troxler TJ, Schmid P, Danner S, Schnell CR, Mueller M, Kinzel B, Grevot A, Bolognani F, Stirn M, Kuhn RR, Kaupmann K, van der Putten PH, Rovelli G, Shimshek DR. Herzig MC, et al. Hum Mol Genet. 2011 Nov 1;20(21):4209-23. doi: 10.1093/hmg/ddr348. Epub 2011 Aug 9. Hum Mol Genet. 2011. PMID: 21828077 Free PMC article.