Mol Cell. 2009 Oct 23;36(2):168-9.

The CST complex and telomere maintenance: the exception becomes the rule.

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Department of Microbiology and Infectious Diseases, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada. raymund.wellinger@usherbrooke.ca

Abstract

Telomeres are bound and stabilized by two complexes-CST and shelterin-thought to be species specific and virtually unrelated. In this issue of Molecular Cell, Miyake et al. (2009) and Surovtseva et al. (2009) provide evidence that these complexes coexist and function at telomeres in many species.

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RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. [Mol Cell. 2009]
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