Gastroenterology. 1991 Feb;100(2):450-7.

A controlled trial of psychological treatment for the irritable bowel syndrome.

Guthrie E, Creed F, Dawson D, Tomenson B.

Source

Department of Psychiatry, Manchester Royal Infirmary, England.

Abstract

One hundred two patients with irritable bowel syndrome were studied in a controlled trial of psychological treatment involving psychotherapy, relaxation, and standard medical treatment compared with standard medical treatment alone. Patients were only selected if their symptoms had not improved with standard medical treatment over the previous 6 months. At 3 months, the treatment group showed significantly greater improvement than the controls on both gastroenterologists' and patients' ratings of diarrhea and abdominal pain, but constipation changed little. Good prognostic factors included overt psychiatric symptoms and intermittent pain exacerbated by stress, whereas those with constant abdominal pain were helped little by this treatment. This study has demonstrated that psychological treatment is feasible and effective in two thirds of those patients with irritable bowel syndrome who do not respond to standard medical treatment.

Comment in

Gastroenterology. 1992 Feb;102(2):739-40.

PMID:: 1985041; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Education

New England Research Institutes Inc.

Medical

Irritable Bowel Syndrome - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Predictive factors of irritable bowel syndrome improvement: 1-year prospective evaluation in 400 patients. [Aliment Pharmacol Ther. 2006]
Predictive factors of irritable bowel syndrome improvement: 1-year prospective evaluation in 400 patients.
Mearin F, Badía X, Balboa A, Benavent J, Caballero AM, Domínguez-Muñoz E, Garrigues V, Piqué JM, Roset M, Cucala M, et al. Aliment Pharmacol Ther. 2006 Mar 15; 23(6):815-26.
A randomised controlled trial of psychotherapy in patients with refractory irritable bowel syndrome. [Br J Psychiatry. 1993]
A randomised controlled trial of psychotherapy in patients with refractory irritable bowel syndrome.
Guthrie E, Creed F, Dawson D, Tomenson B. Br J Psychiatry. 1993 Sep; 163:315-21.
Cognitive-behavioral group therapy for irritable bowel syndrome: effects and long-term follow-up. [Psychosom Med. 1996]
Cognitive-behavioral group therapy for irritable bowel syndrome: effects and long-term follow-up.
van Dulmen AM, Fennis JF, Bleijenberg G. Psychosom Med. 1996 Sep-Oct; 58(5):508-14.
Review Management of irritable bowel syndrome. [Am Fam Physician. 2002]
Review Management of irritable bowel syndrome.
Viera AJ, Hoag S, Shaughnessy J. Am Fam Physician. 2002 Nov 15; 66(10):1867-74.
Review Irritable bowel syndrome: update on pathogenesis and management. [Med Princ Pract. 2002]
Review Irritable bowel syndrome: update on pathogenesis and management.
Alaradi O, Barkin JS. Med Princ Pract. 2002 Jan-Mar; 11(1):2-17.

See reviews... See all...

Cited by 21 PubMed Central articles

Norepinephrine mediates the transcriptional effects of heterotypic chronic stress on colonic motor function. [Am J Physiol Gastrointest Live...]
Norepinephrine mediates the transcriptional effects of heterotypic chronic stress on colonic motor function.
Choudhury BK, Shi XZ, Sarna SK. Am J Physiol Gastrointest Liver Physiol. 2009 Jun; 296(6):G1238-47. Epub 2009 Apr 9.
Five personality dimensions in patients with irritable bowel syndrome. [Neuropsychiatr Dis Treat. 2008]
Five personality dimensions in patients with irritable bowel syndrome.
Farnam A, Somi MH, Sarami F, Farhang S. Neuropsychiatr Dis Treat. 2008 Oct; 4(5):959-62.
Bacterial overgrowth and irritable bowel syndrome: unifying hypothesis or a spurious consequence of proton pump inhibitors? [Am J Gastroenterol. 2008]
Bacterial overgrowth and irritable bowel syndrome: unifying hypothesis or a spurious consequence of proton pump inhibitors?
Spiegel BM, Chey WD, Chang L. Am J Gastroenterol. 2008 Dec; 103(12):2972-6.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

A controlled trial of psychological treatment for the irritable bowel syndrome.
A controlled trial of psychological treatment for the irritable bowel syndrome.
Gastroenterology. 1991 Feb ;100(2):450-7.

PubMed
A brief account of the life of René Le Fort.
A brief account of the life of René Le Fort.
Br J Oral Maxillofac Surg. 2010 Apr ;48(3):173-5. Epub 2009 Oct 21 .

PubMed
Primary microcephaly: do all roads lead to Rome?
Primary microcephaly: do all roads lead to Rome?
Trends Genet. 2009 Nov ;25(11):501-10. Epub 2009 Oct 21 .

PubMed
Proximal esophageal pH-metry in patients with 'reflux laryngitis'.
Proximal esophageal pH-metry in patients with 'reflux laryngitis'.
Gastroenterology. 1991 Feb ;100(2):305-10.

PubMed
An automated method for the determination of the sFlt-1/PIGF ratio in the assess...
An automated method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsia.
Am J Obstet Gynecol. 2010 Feb ;202(2):161.e1-161.e11. Epub 2009 Oct 21 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

A controlled trial of psychological treatment for the irritable bowel syndrome.

Source

Abstract

Comment in

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Education

Medical

Supplemental Content

Save items

Related citations in PubMed

Cited by 21 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information