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Bioinformatics. 2009 Dec 15;25(24):3317-8. doi: 10.1093/bioinformatics/btp586. Epub 2009 Oct 21.

CRISPI: a CRISPR interactive database.

Author information

  • 1IRISA-INRIA, Campus de Beaulieu, 35042 Rennes cedex, France. croussea@irisa.fr; jnicolas@irisa.fr

Abstract

SUMMARY:

The CRISPR genomic structures (Clustered Regularly Interspaced Short Palindromic Repeats) form a family of repeats that is largely present in archaea and frequent in bacteria. On the basis of a formal model of CRISPR using very few parameters, a systematic study of all their occurrences in all available genomes of Archaea and Bacteria has been carried out. This has resulted in a relational database, CRISPI, which also includes a complete repertory of associated CRISPR-associated genes (CAS). A user-friendly web interface with many graphical tools and functions allows users to extract results, find CRISPR in personal sequences or calculate sequence similarity with spacers.

AVAILABILITY:

CRISPI free access at http://crispi.genouest.org

CONTACT:

croussea@irisa.fr; jnicolas@irisa.fr

PMID:
19846435
[PubMed - indexed for MEDLINE]
PMCID:
PMC2788928
Free PMC Article

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