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Nat Immunol. 2009 Nov;10(11):1141-3. doi: 10.1038/ni1109-1141.

The gut feeling of Treg cells: IL-10 is the silver lining during colitis.


Regulatory T cells that express the transcription factor Foxp3 are pivotal in suppressing autoimmune responses. A report in this issue describes a key role for interleukin 10 produced by lamina propria macrophages in maintaining Foxp3 expression during inflammatory responses in the intestine.

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