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Neuron. 2009 Oct 15;64(1):21-4. doi: 10.1016/j.neuron.2009.09.034.

Harnessing immune alterations in neurodegenerative diseases.

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  • 1Neuronal Survival Unit, Department of Experimental Medical Sciences, Wallenberg Neuroscience Center, Lund University, S-221 84 Lund, Sweden.


Immune dysfunction, a well-established feature of neuroinflammatory disease, is increasingly recognized in neurodegenerative conditions. Its role is emerging as an early and active participant in neuropathology. Inflammation could be modified, with disease-slowing effects, by targeted interventions; it is also readily detectable and could serve as a source of valuable biomarkers.

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