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Immunity. 2009 Oct 16;31(4):536-8. doi: 10.1016/j.immuni.2009.09.005.

Gut immune balance is as easy as S-F-B.

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  • 1Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.


Microbes appear to modulate homeostatic plasticity of T helper and T regulatory cells. In this issue of Immunity, Gaboriau-Routhiau et al. (2009) now reveal that segmented filamentous bacteria uniquely coordinate the intestinal T cell profile. The potential implications of this process to various immune functions are discussed.

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