The additive value of patch testing with patients' own products at an occupational dermatology clinic

Contact Dermatitis. 2009 Oct;61(4):231-5. doi: 10.1111/j.1600-0536.2009.01610.x.

Abstract

Background and objectives: Patch testing with commercially available kits detects only 70-80% of relevant allergens in patients with contact dermatitis. This is not ideal, especially when occupational issues are being evaluated. This study analyses our data regarding reactions to patients' own products.

Methods: In a 5-year period, 1532 patients were assessed in our occupational dermatology clinic.

Results: We found that 101 patients (6.6%) reacted to their own samples. In 20 (1.3%) cases, reacting to their own samples was the only clue for detecting the responsible allergen. In 59 (3.9%) cases, testing with their own samples reinforced their reactions to commercial allergens.

Conclusions: We found the overall additive value of testing with patients' own products to be 5.2%. This is not a low proportion considering the 20-30% false negative rate when patch testing. Patch testing with patients' own samples, appropriately diluted should be undertaken whenever possible.

MeSH terms

  • Adult
  • Aged
  • Allergens* / immunology
  • Australia
  • Chi-Square Distribution
  • Dermatitis, Occupational / diagnosis*
  • Dermatitis, Occupational / immunology
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Middle Aged
  • Occupational Exposure / adverse effects
  • Occupations
  • Patch Tests / methods*

Substances

  • Allergens