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Sao Paulo Med J. 2009;127(3):174-6.

Hemosiderotic fibrohistiocytic lipomatous lesion: case report and review of the literature.

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  • 1Universidade Federal do Triângulo Mineiro (UFTM), Minas Gerais, Brazil.



Lesions of the adipose tissue are the most common type of soft-tissue lesion among adults.


We describe the case of a 33-year-old female patient with a soft-tissue lesion in her left knee that was diagnosed as a hemosiderotic fibrohistiocytic lipomatous lesion. This type of lesion, which was described for the first time in 2000, preferentially affects the ankle region of middle-aged women with a history of previous local trauma. Lesion recurrence is common, caused by incomplete resection, although there have not yet been any reports of metastases. After a review of the literature, we describe the clinical, radiological, morphological and immunohistochemical characteristics, along with their main differential diagnoses.

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