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Genome Biol. 2009;10(10):R109. doi: 10.1186/gb-2009-10-10-r109. Epub 2009 Oct 8.

A compiled and systematic reference map of nucleosome positions across the Saccharomyces cerevisiae genome.

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  • 1Department of Biochemistry and Molecular Biology, Center for Eukaryotic Gene Regulation, 456 North Frear Laboratory, The Pennsylvania State University, University Park, PA 16802, USA. czjiang@tongji.edu.cn


Nucleosomes have position-specific functions in controlling gene expression. A complete systematic genome-wide reference map of absolute and relative nucleosome positions is needed to minimize potential confusion when referring to the function of individual nucleosomes (or nucleosome-free regions) across datasets. We compiled six high-resolution genome-wide maps of Saccharomyces cerevisiae nucleosome positions from multiple labs and detection platforms, and report new insights. Data downloads, reference position assignment software, queries, and a visualization browser are available online http://atlas.bx.psu.edu/.

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