Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age

J Perinatol. 2010 Apr;30(4):281-5. doi: 10.1038/jp.2009.147. Epub 2009 Oct 8.

Abstract

Objective: Our aim was to determine the incidence of anatomical abnormalities after a urinary tract infection (UTI) in infants <2 months of age hospitalized in the neonatal intensive care unit (NICU).

Study design: This was a retrospective, single-center cohort study of infants <2 months of age in the NICU with a UTI and documented renal imaging.

Result: We identified 141 infants with UTIs. The mean gestational age and birth weight were 28 weeks and 1254 g, respectively. The most commonly identified pathogen was coagulase-negative Staphylococcus (28%, 44 of 156). A major abnormality was found on at least one imaging study for 4% (5 of 118) of infants. Major abnormalities were noted on 4% (5 of 114) of renal ultrasounds and 2% (2 of 82) of voiding cystourethrography examinations.

Conclusion: Among infants in the NICU <2 months of age at the time of a UTI, the prevalence of major anatomical abnormalities is <5%.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Academic Medical Centers / statistics & numerical data
  • Female
  • Humans
  • Hydronephrosis / complications*
  • Hydronephrosis / diagnostic imaging
  • Hydronephrosis / epidemiology*
  • Infant
  • Infant, Newborn
  • Intensive Care Units, Neonatal / statistics & numerical data
  • Male
  • North Carolina / epidemiology
  • Prevalence
  • Ultrasonography
  • Urinary Tract Infections / complications*
  • Urogenital Abnormalities / complications*
  • Urogenital Abnormalities / diagnostic imaging
  • Urogenital Abnormalities / epidemiology*