Abstract
Membrane marker techniques, endocytosis, and cytochemical methods were used to characterize L5178Y cells. L5178Y cells were found to have surface membrane immunoglobulin that typifies B-cells, and membrane receptors that are common to both B-cells and monocytes. L5178Y cells also have endocytic and enzymatic activities that are characteristic of monocytes. Thus L5178Y cells have the dual characteristics of B-cells and monocytes.
MeSH terms
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Animals
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B-Lymphocytes / immunology
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B-Lymphocytes / pathology*
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Cell Line
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Cell Membrane / immunology
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Endocytosis*
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Immunoglobulin Fc Fragments
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Inclusion Bodies, Viral
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Leukemia, Experimental / immunology
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Leukemia, Experimental / pathology*
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Leukemia, Experimental / physiopathology
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Monocytes / immunology
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Monocytes / pathology*
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Receptors, Antigen, B-Cell
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Retroviridae
Substances
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Immunoglobulin Fc Fragments
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Receptors, Antigen, B-Cell