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Expert Rev Neurother. 2003 Jul;3(4):425-33. doi: 10.1586/14737175.3.4.425.

Mirtazapine in the treatment of mood and anxiety disorders.

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  • 1The Harvard Bipolar Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.


Mirtazapine is a new antidepressant whose effects on presynaptic adrenergic receptors leads to increased serotonergic transmission, and thus its antidepressant and antianxiety effects. It is equal in practical effectiveness to any currently marked antidepressant but may exert its effects earlier than some others. It is safe, well-tolerated and a useful addition to the drugs currently available for the treatment of mood and anxiety disorders.

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