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Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination.
Chi XZ, Kim J, Lee YH, Lee JW, Lee KS, Wee H, Kim WJ, Park WY, Oh BC, Stein GS, Ito Y, van Wijnen AJ, Bae SC.
Cancer Res. 2009 Oct 15;69(20):8111-9. Epub 2009 Oct 6.
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Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation.
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