Send to:

Choose Destination
See comment in PubMed Commons below
J Clin Biochem Nutr. 2009 Sep;45(2):214-8. doi: 10.3164/jcbn.08-261. Epub 2009 Aug 28.

Fungicidal action of hydroxyl radicals generated by ultrasound in water.

Author information

  • 1Tissue Culture Laboratory, Showa University Fujigaoka Hospital, 1-30, Fujigaoka, Aoba-ku, Yokohama, Kanagawa 227-8501, Japan.


It is well known that hydroxyl radicals are generated by ultrasound in water. This study with an electron spin resonance spin-trapping technique showed that hydroxyl radical generation was positively correlated with ultrasound duration and water temperature. The clear fungicidal action against Trichophyton spp. evident by studying cultured cells and the degradation of cytoplasmic and surface structures observed by transmission and scanning electron microscopy suggest that ultrasound in hot water is effective for sterilization of dermatophyte contamination and could be effective for the treatment of tinea infection.


Trichophyton spp.; electron microscopy; fungicidal activity; hydroxyl radical; ultrasound

Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for J-STAGE, Japan Science and Technology Information Aggregator, Electronic Icon for PubMed Central
    Loading ...
    Write to the Help Desk