MPEx screen shots. (A) MPEx in translocon TM analysis mode. The window consists of three main sections: The top portion provides standard application type pull-down menus for operations like I/O or functions common across different analysis modes, data buffer controls, and tabs for analysis mode selection. The white region to the lower left displays analysis plots, and the shaded region to the right contains the data summary window and control panel. The control panel allows selecting the plotting region cursor location, the sliding window size range, and changing or restoring a changed residue in the current analysis sequence. (B) Results window for translocon TM analysis, displaying control settings, analysis results, and working amino acid sequence. (C) MPEx in totalizer mode. Totalizer mode is primarily for the analysis of short amino acid sequences and the design of membrane-active peptides. Totalizer generates a helical wheel display for the sequence being examined, along with an arrow indicating the direction and relative magnitude of the hydrophobic moment for the sequence.