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J Med Microbiol. 2010 Jan;59(Pt 1):17-24. doi: 10.1099/jmm.0.012336-0.

VopF, a type III effector protein from a non-O1, non-O139 Vibrio cholerae strain, demonstrates toxicity in a Saccharomyces cerevisiae model.

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  • 1Institute of Microbial Technology, Molecular Biology Division, Chandigarh, Council of Scientific and Industrial Research (CSIR), New Delhi, India.


VopF, a type III effector protein, has been identified as a contributory factor to the intestinal colonization of type III secretion system-positive, non-O1, non-O139 Vibrio cholerae strains. To gain more insight into the function of VopF, a yeast model was developed. Using this model, it was found that ectopic expression of VopF conferred toxicity in yeast.

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