Display Settings:

Format

Send to:

Choose Destination
Org Lett. 2009 Oct 15;11(20):4748-51. doi: 10.1021/ol901961q.

Revealing substrate promiscuity of 1-deoxy-D-xylulose 5-phosphate synthase.

Author information

  • 1Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Abstract

A study of DXP synthase has revealed flexibility in the acceptor substrate binding pocket for nonpolar substrates and has uncovered new details of the catalytic mechanism to show that pyruvate can act as both donor and acceptor substrate.

PMID:
19778006
[PubMed - indexed for MEDLINE]
PMCID:
PMC2761658
Free PMC Article

Images from this publication.See all images (3)Free text

Figure 1
Figure 2
Figure 3
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society Icon for PubMed Central
    Loading ...
    Write to the Help Desk