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The human aminopeptidase N gene: isolation, chromosome localization, and DNA polymorphism analysis.
Department of Physiology, University of Toronto, Ontario, Canada.
DNA encoding the human aminopeptidase N (EC 3.4.11.2) gene (PEPN) was first isolated using rat cDNA probes and then used in Southern analysis of DNA from mouse-human somatic cell hybrids to assign this gene to the long-arm region (q11-qter) of human chromosome 15. This human genomic DNA probe detects a frequent DraIII polymorphism that is a useful marker for human chromosome 15.
PMID: 1977688 [PubMed - indexed for MEDLINE]
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Cited by 2 PubMed Central articles
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The Drosophila slamdance gene: a mutation in an aminopeptidase can cause seizure, paralysis and neuronal failure.
Zhang H, Tan J, Reynolds E, Kuebler D, Faulhaber S, Tanouye M.
Genetics. 2002 Nov; 162(3):1283-99.
[Genetics. 2002]
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Induction of the membrane alanyl aminopeptidase gene and surface expression in human T-cells by mitogenic activation.
Lendeckel U, Wex T, Reinhold D, Kähne T, Frank K, Faust J, Neubert K, Ansorge S.
Biochem J. 1996 Nov 1; 319 ( Pt 3):817-21.
[Biochem J. 1996]