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    J Cutan Pathol. 2009 Oct;36 Suppl 1:16-9.

    Ulcerated dermatofibroma with osteoclast-like giant cells.

    Source

    Department of Dermatology, Complejo Hospitalario Universitario, Faculty of Medicine, Santiago de Compostela, Spain. jaime.toribio@usc.es

    Abstract

    BACKGROUND:

    Ulceration and osteoclast-like giant cells are two pathological features uncommonly seen in dermatofibromas. To our knowledge, the presence of these features has not been previously described within the same lesion.

    METHODS:

    We report the clinical, histopathological and immunohistochemical findings of a 38-year-old man with an ulcerated dermatofibroma (DF) on the sole containing OLGC.

    COMMENTS:

    DF, or cutaneous fibrous histiocytoma, is a frequent dermatological lesion with many clinicopathological variants. Therefore, a correct diagnosis is not always straightforward, especially when two rare features co-exist in the same lesion. Differential diagnosis was performed with cutaneous and even non-cutaneous lesions. An explanation for the clinicopathological findings is also described.

    PMID:
    19775390
    [PubMed - indexed for MEDLINE]

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